Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010622 | 0.95 | VDR (0.56) | VDRCYP24A1 | |
| SCHEMBL14357531 | 0.95 | VDR (0.56) | VDRCYP24A1 | |
| SCHEMBL10125580 | 0.92 | VDR (0.51) | VDR | |
| SCHEMBL9010570 | 0.92 | VDR (0.51) | VDR | |
| SCHEMBL12190441 | 0.92 | VDR (0.51) | VDRCYP24A1 | |
| SCHEMBL9010583 | 0.90 | VDR (0.57) | VDRCYP24A1 | |
| SCHEMBL14728279 | 0.90 | VDR (0.49) | VDR | |
| SCHEMBL14728295 | 0.90 | VDR (0.49) | VDR | |
| SCHEMBL10125575 | 0.90 | VDR (0.51) | VDR | |
| SCHEMBL10125530 | 0.90 | VDR (0.51) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018021-A1 | 2Alpha-Methyl and 2Beta-Methyl Analogs of 19,26,27-Trinor-(20S)-1Alpha-Hydroxyvitamin D3 and Their Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018021-A1 | 2Alpha-Methyl and 2Beta-Methyl Analogs of 19,26,27-Trinor-(20S)-1Alpha-Hydroxyvitamin D3 and Their Uses | CYP24A1, CYP27B1, CD14 | VDR 4/4885CYP24A1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.