Styrene

Styrene

SCHEMBL9010621

C=C(C)C(=O)OCCS(=O)(=O)O.C=Cc1ccccc1

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
POLB P06746 2/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TSHR P16473 3/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
THRB P10828 2/20 0.36
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
MCL1 Q07820 1/20 0.35
ELANE P08246 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7037322 0.93 TSHR (0.46) TDP1POLBAPEX1HTTALDH1A1
Styrene SCHEMBL8361059 0.87 THRB (0.47) TDP1POLBAPEX1HTTALDH1A1
SCHEMBL4566748 0.87 TDP1 (0.54) TDP1POLBAPEX1HTTTSHR
SCHEMBL28211115 0.86 PPARG (0.39) TDP1POLBAPEX1HTTALDH1A1
Vinylsulfonic Acid SCHEMBL28072676 0.85 PPARG (0.37) TDP1POLBAPEX1HTTALDH1A1
Styrene SCHEMBL6562348 0.84 TDP1 (0.50) TDP1POLBAPEX1HTTALDH1A1
Styrene SCHEMBL409075 0.83 TDP1 (0.43) TDP1POLBAPEX1HTTALDH1A1
Styrene SCHEMBL21715490 0.83 THRB (0.44) TDP1POLBAPEX1HTTALDH1A1
Styrene SCHEMBL9305623 0.83 TDP1 (0.43) TDP1POLBAPEX1HTTALDH1A1
Styrene SCHEMBL5864400 0.83 TSHR (0.46) TDP1POLBAPEX1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2906330-A1 COATED ION EXCHANGE MEMBRANES Evoqua Water Technologies LLC (US) 2015-08-19 EP disclosed
EP-2903737-A1 HIGH-PERFORMANCE ANION EXCHANGE MEMBRANES AND METHODS OF MAKING SAME Evoqua Water Technologies LLC (US) 2015-08-12 EP disclosed
WO-2014055123-A1 HIGH-PERFORMANCE ANION EXCHANGE MEMBRANES AND METHODS OF MAKING SAME EVOQUA WATER TECHNOLOGIES LLC (US) 2014-04-10 WO disclosed
EP-0604859-B1 Thermal dye transfer receiving element with antistat backing layer EASTMAN KODAK CO (US) 1996-10-23 EP disclosed
EP-0604859-A2 Thermal dye transfer receiving element with antistat backing layer EASTMAN KODAK COMPANY (US) 1994-07-06 EP disclosed
US-5252535-A Comprising an anionic addition polymer, colloid particles and polymer beads; antisticking agents; adequate friction for a thermal printer rubber pick roll EASTMAN KODAK COMPANY (US) 1993-10-12 US disclosed