SCHEMBL687865

SCHEMBL687865

O=C(Oc1ccc(O)cc1)c1cccc(C(=O)Oc2ccc(O)cc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.56
ESR1 P03372 3/20 0.56
ESR2 Q92731 2/20 0.56
MEN1 O00255 4/20 0.55
CASP3 P42574 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
MAPT P10636 5/20 0.51
TDP1 Q9NUW8 3/20 0.51
PARP10 Q53GL7 1/20 0.50
NSD2 O96028 1/20 0.50
MAPK1 P28482 2/20 0.49
KDM4E B2RXH2 1/20 0.49
LMNA P02545 1/20 0.47
SERPINE1 P05121 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 1/20 0.47
PKM P14618 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11871223 0.94 MAPT (0.59) KMT2AESR1ESR2MEN1CASP3
SCHEMBL10456285 0.94 MAPT (0.59) KMT2AESR1ESR2MEN1CASP3
SCHEMBL9435811 0.93 CA12 (0.53) KMT2AESR1ESR2MEN1CASP3
SCHEMBL9010694 0.92 ESR1 (0.61) KMT2AESR1ESR2MEN1CASP3
SCHEMBL10456284 0.88 LMNA (0.57) KMT2AESR1ESR2MEN1CASP3
SCHEMBL21681878 0.88 ESR1 (0.65) KMT2AESR1ESR2MEN1CASP3
SCHEMBL21500895 0.88 KMT2A (0.50) KMT2AESR1ESR2MEN1CASP3
SCHEMBL10875111 0.87 MAPT (0.56) KMT2AESR1ESR2MEN1CASP3
SCHEMBL28818159 0.86 ESR1 (0.77) KMT2AESR1ESR2MEN1CASP3
SCHEMBL21465315 0.86 PARP10 (0.50) KMT2AESR1ESR2MEN1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3008104-A2 BIO-OIL POLYOLS, ALKOXYLATED BIO-OIL POLYOLS AND BIO-OIL PHENOLIC RESINS Battelle Memorial Institute (US) 2016-04-20 EP claimed
WO-2014201185-A2 BIO-OIL POLYOLS, ALKOXYLATED BIO-OIL POLYOLS AND BIO-OIL PHENOLIC RESINS BATTELLE MEMORIAL INSTITUTE (US) 2014-12-18 WO claimed
EP-0848025-A2 A process for forming a finish surface on a composite material BATTELLE MEMORIAL INSTITUTE (US) 1998-06-17 EP claimed
US-9464183-B2 Rubber composition and pneumatic tire using the same BRIDGESTONE CORPORATION (JP) 2016-10-11 US disclosed
US-20160145285-A1 Bio-Oil Polyols, Alkoxylated Bio-Oil Polyols and Bio-Oil Phenolic Resins BATTELLE MEMORIAL INSTITUTE 2016-05-26 US disclosed
EP-3008104-A2 BIO-OIL POLYOLS, ALKOXYLATED BIO-OIL POLYOLS AND BIO-OIL PHENOLIC RESINS Battelle Memorial Institute (US) 2016-04-20 EP disclosed
WO-2014201185-A2 BIO-OIL POLYOLS, ALKOXYLATED BIO-OIL POLYOLS AND BIO-OIL PHENOLIC RESINS BATTELLE MEMORIAL INSTITUTE (US) 2014-12-18 WO disclosed
US-8222446-B2 Method for producing dihydroxybenzene derivative MITSUI CHEMICALS, INC. (JP) 2012-07-17 US disclosed
EP-1820667-B1 PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2012-02-29 EP disclosed
CN-101076457-B Pneumatic tire BRIDGESTONE CORP 2011-07-27 CN disclosed
EP-1724302-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME BRIDGESTONE CORP (JP) 2011-07-20 EP disclosed
US-5239039-A Reacting an excess of hydrogen cyanide with an aryl diisocyanate; adding more diisocyanate and a dihydric phenol; crosslinking inhibition; thermally reversible; melt processible coatings and adhesives BATTELLE MEMORIAL INSTITUTE (US) 1993-08-24 US disclosed
WO-1993003080-A2 THERMALLY REVERSIBLE ISOCYANATE-BASED POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1993-02-18 WO disclosed
EP-0514459-A1 THERMALLY-REVERSIBLE ISOCYANATE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-25 EP disclosed
US-5097010-A Thermally-reversible isocyanate polymers BATTELLE MEMORIAL INSTITUTE (US) 1992-03-17 US disclosed
WO-1991011476-A2 THERMALLY-REVERSIBLE ISOCYANATE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1991-08-08 WO disclosed
EP-0052927-B1 STRETCHED FILM STRUCTURE OF THE POLY-1,3-PHENYLENE TEREPHTHALATE TYPE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-01-07 EP disclosed
EP-0015828-B1 STRESS-CRACK RESISTANT POLYARYLATES AND PROCESS FOR THE PREPARATION UNION CARBIDE CORPORATION (US) 1983-07-13 EP disclosed
US-4275188-A POLYESTERS OF TEREPHTHALIC ACID, ISOPHTHALIC ACID, BISPHENOLS AND BIPHENOL ARE MELT PROCESSABLE AND HAVE GOOD SOLVENT RESISTANCE UNION CARBIDE CORPORATION (US) 1981-06-23 US disclosed
EP-0015828-A1 Stress-crack resistant polyarylates and process for the preparation UNION CARBIDE CORPORATION (US) 1980-09-17 EP disclosed