SCHEMBL9010699

SCHEMBL9010699

COc1ccccc1C(=O)Oc1ccc(O)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.72
ESR1 P03372 3/20 0.72
MEN1 O00255 2/20 0.72
MAPT P10636 4/20 0.70
HPGD P15428 3/20 0.70
NPSR1 Q6W5P4 2/20 0.70
XBP1 P17861 1/20 0.70
ESR2 Q92731 2/20 0.57
LMNA P02545 1/20 0.56
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP3A4 P08684 1/20 0.54
GAA P10253 2/20 0.54
TP53 P04637 1/20 0.54
HSD17B10 Q99714 2/20 0.50
ALOX15 P16050 1/20 0.50
ATM Q13315 1/20 0.50
PTGS2 P35354 1/20 0.50
TYR P14679 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4389475 0.88 NPSR1 (0.72) KMT2AESR1MEN1MAPTHPGD
SCHEMBL2149614 0.88 MAPT (0.71) KMT2AESR1MEN1MAPTHPGD
SCHEMBL10909900 0.86 KMT2A (0.71) KMT2AESR1MEN1MAPTHPGD
SCHEMBL7184670 0.85 KMT2A (0.54) KMT2AESR1MEN1MAPTHPGD
SCHEMBL16675179 0.84 HPGD (0.67) KMT2AESR1MEN1MAPTHPGD
SCHEMBL9683161 0.84 MAPT (0.67) KMT2AESR1MEN1MAPTHPGD
SCHEMBL1547850 0.84 KMT2A (0.68) KMT2AESR1MEN1MAPTHPGD
SCHEMBL9724321 0.84 KMT2A (0.63) KMT2AESR1MEN1MAPTHPGD
SCHEMBL28055670 0.83 KMT2A (0.59) KMT2AESR1MEN1MAPTHPGD
SCHEMBL16599350 0.83 MAPT (0.65) KMT2AESR1MEN1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5519106-A COLORLESS MITSUBISHI CHEMICAL CORPORATION (JP) 1996-05-21 US disclosed
US-5455324-A Containing reduced amounts of benzophenone and benzoate ester derivatives MITSUBISHI CHEMICAL CORPORATION (JP) 1995-10-03 US disclosed
EP-0584801-A2 Aromatic polycarbonate resins and process for the preparation thereof Mitsubishi Chemical Corporation (JP) 1994-03-02 EP disclosed
US-4410619-A SULFINIC ACID OR SULFINATE DISCOLORATION INHIBITOR MITSUBISHI PAPER MILLS, LTD. (JP) 1983-10-18 US disclosed