⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010725 | 0.92 | PPARG (0.32) | — | |
| SCHEMBL14107872 | 0.82 | STAT3 (0.32) | — | |
| SCHEMBL9010727 | 0.82 | — | — | |
| SCHEMBL2703984 | 0.81 | VDR (0.31) | — | |
| SCHEMBL9010728 | 0.79 | — | — | |
| SCHEMBL12857870 | 0.76 | — | — | |
| SCHEMBL2701897 | 0.75 | VDR (0.35) | — | |
| SCHEMBL9010750 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL14469749 | 0.73 | — | — | |
| SCHEMBL6429594 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-7531527-B2 | 2-Propylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-12 | — | — | US | disclosed |
| US-20070213546-A1 | 2-Propylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION. (US) | 2007-09-13 | — | — | US | disclosed |
| US-7241747-B2 | 2-propylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-07-10 | — | — | US | disclosed |