SCHEMBL9010788

SCHEMBL9010788

CC1CCCC(c2ccccc2)OC1=O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.44
CYP19A1 P11511 3/20 0.44
KDM4E B2RXH2 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
AR P10275 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HSD11B1 P28845 2/20 0.40
TSHR P16473 1/20 0.39
MAOA P21397 1/20 0.38
PSMB5 P28074 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17882107 0.89 MAOB (0.42) MAOBCYP19A1KDM4EADORA3AR
SCHEMBL6288848 0.80 TSHR (0.43) MAOBCYP19A1KDM4EADORA3AR
SCHEMBL5936332 0.80 TSHR (0.43) MAOBCYP19A1KDM4EADORA3AR
SCHEMBL18099888 0.80 TSHR (0.43) MAOBCYP19A1KDM4EADORA3AR
SCHEMBL28354123 0.73 TSHR (0.43) MAOBCYP19A1KDM4EADORA3AR
SCHEMBL2743656 0.73 TSHR (0.43) MAOBCYP19A1KDM4EADORA3AR
SCHEMBL19389714 0.72 SLC6A3 (0.42) MAOB
SCHEMBL1331244 0.71 KDM4E (0.42) MAOBCYP19A1KDM4EADORA3AR
SCHEMBL15883776 0.71 KDM4E (0.42) MAOBCYP19A1KDM4EADORA3AR
SCHEMBL17860839 0.71 MAOB (0.42) MAOBCYP19A1KDM4EADORA3AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0477983-B1 Unsaturated polylactone acrylates and derivatives thereof UNION CARBIDE CHEM PLASTIC (US) 1996-11-13 EP disclosed
US-5557007-A Unsaturated polylactone acrylates and derivatives thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-09-17 US disclosed
EP-0235704-B1 Carboxyl-terminated lactone acrylates UNION CARBIDE CORP (US) 1994-03-30 EP disclosed
EP-0477983-A2 Unsaturated polylactone acrylates and derivatives thereof UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-04-01 EP disclosed
US-4786749-A RADIATION CURABLE MONOMERS FOR COATINGS, INKS, ADHESIVES, DISPERSANTS, HARDENERS UNION CARBIDE CORPORATION (US) 1988-11-22 US disclosed
EP-0235704-A2 Carboxyl-terminated lactone acrylates UNION CARBIDE CORPORATION (US) 1987-09-09 EP disclosed