SCHEMBL1331244

SCHEMBL1331244

O=C1CCCCC(c2ccccc2)O1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
AR P10275 1/20 0.42
CYP19A1 P11511 1/20 0.42
MAOB P27338 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TSHR P16473 1/20 0.42
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
SLC18A3 Q16572 1/20 0.41
GAA P10253 1/20 0.40
ATM Q13315 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NOS1 P29475 2/20 0.39
NOS2 P35228 2/20 0.39
MCL1 Q07820 1/20 0.39
HSD11B1 P28845 2/20 0.38
CTRB1 P17538 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15883776 1.00 KDM4E (0.42) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL2743656 0.94 TSHR (0.43) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL28354123 0.94 TSHR (0.43) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL9012682 0.86 TSHR (0.46) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL7339250 0.86 TSHR (0.46) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL982856 0.86 TSHR (0.46) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL28978626 0.84 MAOB (0.41) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL7550704 0.80 CYP19A1 (0.49) CYP19A1
SCHEMBL21784182 0.80 MAOB (0.33) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL15322578 0.78 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1438368-B1 PHOTOCHROMIC POLYMERIZABLE COMPOSITIONS TRANSITIONS OPTICAL INC (US) 2008-02-20 EP claimed
US-6998072-B2 Containing polymerizable material and photochromic compound; ophthalmic lenses TRANSITIONS OPTICAL, INC. (US) 2006-02-14 US claimed
US-6916537-B2 Articles having a photochromic polymeric coating TRANSITIONS OPTICAL INC. (US) 2005-07-12 US claimed
EP-1451256-B1 ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING TRANSITIONS OPTICAL INC (US) 2005-06-29 EP claimed
EP-1451256-A1 ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING TRANSITIONS OPTICAL, INC. (US) 2004-09-01 EP claimed
US-20030143404-A1 Articles having a photochromic polymeric coating TRANSITIONS OPTICAL LIMITED (IE) 2003-07-31 US claimed
US-20030136948-A1 Photochromic polymerizable compositions TRANSITIONS OPTICAL LIMITED (IE) 2003-07-24 US claimed
WO-2003037998-A1 ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING TRANSITIONS OPTICAL, INC. (US) 2003-05-08 WO claimed
CN-119731020-A Multilayer structure, method for producing same, automobile component, aircraft component, and vibration-resistant material for carbon fiber reinforced plastic 三菱化学株式会社 2025-03-28 CN disclosed
CN-115298263-B Resin composition, molded article, modifier for polyamide resin, and method for modifying polyamide resin 三菱化学株式会社 2024-10-25 CN disclosed
CN-118765305-A Modified ethylene-vinyl alcohol copolymer composition, pellet, multilayer structure, method for producing modified ethylene-vinyl alcohol copolymer composition, and method for producing multilayer structure 三菱化学株式会社 2024-10-11 CN disclosed
US-20240199866-A1 RESIN COMPOSITION, MOLDED ARTICLE, MODIFIER FOR ABS RESIN, METHOD FOR MANUFACTURING RESIN COMPOSITION, AND METHOD FOR MODIFYING ABS RESIN MITSUBISHI CHEMICAL CORPORATION (JP) 2024-06-20 US disclosed
CN-117836367-A Resin composition, molded article, modifier for ABS resin, method for producing resin composition, and method for modifying ABS resin 三菱化学株式会社 2024-04-05 CN disclosed
WO-2024071139-A1 MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME, AUTOMOBILE PART, AIRCRAFT PART, AND DAMPING MATERIAL FOR CARBON-FIBER-REINFORCED PLASTIC 三菱ケミカル株式会社 2024-04-04 WO disclosed
EP-0308852-B1 Solid solution CANON KK (JP) 1995-03-08 EP disclosed
EP-0580054-A2 Process for preparing polyhydroxy compounds and their use in paints BAYER AG (DE) 1994-01-26 EP disclosed
US-5032671-A And copolymers with epoxides ARCO CHEMICAL TECHNOLOGY, INC. (US) 1991-07-16 US disclosed
US-4981614-A COMPRISING A MIXTURE OF POLYLACTONE OR NYLON COPOLYMER AND AN ORGANIC GUEST ELECTRONEGATIVE COMPOUND; NONLINEAR OPTICAL DEVICES; FILMS FOR DISPLAYS; CRYSTAL WAVELENGTH CONVERTERS FOR LASERS CANON KABUSHIKI KAISHA (JP) 1991-01-01 US disclosed
EP-0308852-A2 Solid solution CANON KABUSHIKI KAISHA (JP) 1989-03-29 EP disclosed
US-4192938-A Modified polyisocyanates containing sulfonic acid ester groups BAYER AKTIENGESELLSCHAFT (DE) 1980-03-11 US disclosed