Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797751 | 0.87 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| SCHEMBL11142138 | 0.84 | FAAH (0.51) | ALDH1A1HSD17B10FAAHTSHRCES2 | |
| SCHEMBL4879802 | 0.84 | FAAH (0.51) | ALDH1A1HSD17B10FAAHTSHRCES2 | |
| SCHEMBL4883613 | 0.84 | FAAH (0.51) | ALDH1A1HSD17B10FAAHTSHRCES2 | |
| SCHEMBL8612369 | 0.83 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| SCHEMBL21986928 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Alcohol SCHEMBL28292678 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| SCHEMBL9012179 | 0.81 | — | — | |
| SCHEMBL17865658 | 0.80 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| SCHEMBL17865669 | 0.80 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024574-A1 | DNA SEQUENCING WITH NON-FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS AND CLEAVABLE LABEL MODIFIED NUCLEOTIDE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-01-28 | — | — | US | disclosed |
| US-8558012-B2 | 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2013-10-15 | — | — | US | disclosed |
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2011-12-29 | — | — | US | disclosed |
| EP-0243160-B2 | Blocked isocyanatocarbonyl group-containing polymers | NIPPON PAINT CO LTD (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-5274062-A | An N-(substituted oxalyl)-halopropionamide | NIPPON PAINT CO., LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5208308-A | N-Oxalyl-Substituted | NIPPON PAINT CO., LTD. (JP) | 1993-05-04 | — | — | US | disclosed |
| US-4970281-A | COATINGS, ADHESIVES, MOLDING | NIPPON PAINT CO., LTD. (JP) | 1990-11-13 | — | — | US | disclosed |
| US-4956491-A | MONOMERS FOR RESINS USED IN COATINGS, ADHESIVES OR MOLDING MATERIALS | NIPPON PAINT CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| US-4914225-A | MOLDING MATERIALS, COATINGS, ADHESIVES | NIPPON PAINT CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4816537-A | COATINGS, AUTOMOBILES | NIPPON PAINT CO., LTD. (JP) | 1989-03-28 | — | — | US | disclosed |
| EP-0243208-A2 | Acrylamide derivatives and their polymers | Nippon Paint Co., Ltd. (JP) | 1987-10-28 | — | — | EP | disclosed |
| EP-0243207-A2 | Alpha-alkylacrylamide derivatives and their polymers | Nippon Paint Co., Ltd. (JP) | 1987-10-28 | — | — | EP | disclosed |
| EP-0243160-A2 | Blocked isocyanatocarbonyl group-containing polymers | Nippon Paint Co., Ltd. (JP) | 1987-10-28 | — | — | EP | disclosed |
| EP-0015230-B1 | STABILIZED ORGANIC POLYMER COMPRISING 2-(2-HYDROXY-3,5-DI-TERT-OCTYLPHENYL)-2H-BENZOTRIAZOLE AS A LIGHT-STABILIZER | CIBA-GEIGY AG (CH) | 1983-02-23 | — | — | EP | disclosed |
| US-3949007-A | METAL HYDROXIDE OR ALKOXIDE CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | CBR1, CYP1B1, CYP2F1 | ALDH1A1 160/4885LMNA 3752/4885HSD17B10 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.