SCHEMBL9010899

SCHEMBL9010899

Cc1ccc2nn(-c3ccc(O)cc3O)nc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.55
RAB9A P51151 7/20 0.55
LMNA P02545 2/20 0.55
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
POLB P06746 3/20 0.37
ESR1 P03372 2/20 0.37
PDK1 Q15118 1/20 0.36
PDK2 Q15119 1/20 0.36
PDK3 Q15120 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17201891 0.88 NPC1 (0.42) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL11160703 0.87 NPC1 (0.69) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL11375525 0.85 RAB9A (0.44) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL10441256 0.84 NPC1 (0.56) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL28556638 0.83 NPC1 (0.40) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL24454617 0.83 NPC1 (0.54) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL6135958 0.82 NPC1 (0.71) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL22129842 0.82 NPC1 (0.50) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL30162806 0.82 NPC1 (0.50) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL29422754 0.81 NPC1 (0.75) NPC1RAB9ALMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12504568-B2 Photochromic-dichroic articles TRANSITIONS OPTICAL, LTD. (IE) 2025-12-23 US disclosed
EP-4244305-B1 PHOTOCHROMIC-DICHROIC ARTICLES TRANSITIONS OPTICAL LTD (IE) 2025-05-21 EP disclosed
US-20230400616-A1 Photochromic-Dichroic Articles TRANSITIONS OPTICAL, LTD. (IE) 2023-12-14 US disclosed
CN-116391009-A Photochromic-dichroic articles 光学转变有限公司 2023-07-04 CN disclosed
US-5585228-A Benzotriazole based UV absorbing compounds and photographic elements containing them EASTMAN KODAK COMPANY (US) 1996-12-17 US disclosed
EP-0717313-A1 Benzotriazole based UV absorbing compounds and photographic elements containing them EASTMAN KODAK COMPANY (US) 1996-06-19 EP disclosed
US-4271307-A Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1981-06-02 US disclosed
US-4076687-A Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-02-28 US disclosed