Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010964 | 0.87 | CA1 (0.34) | NPC1POLBRAB9ASMN1; SMN2CYP2D6 | |
| SCHEMBL150281 | 0.80 | HDAC8 (0.42) | — | |
| SCHEMBL9010936 | 0.79 | HPGD (0.32) | — | |
| SCHEMBL9011089 | 0.78 | MEN1 (0.42) | NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1980407 | 0.71 | — | — | |
| SCHEMBL17157330 | 0.70 | SLC22A2 (0.38) | POLBSMN1; SMN2KMT2A | |
| Water SCHEMBL4146453 | 0.69 | — | — | |
| SCHEMBL9011152 | 0.69 | KDM4E (0.42) | CYP2D6HSD17B10KMT2A | |
| SCHEMBL29252552 | 0.67 | SMN1; SMN2 (0.47) | NPC1POLBRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9010948 | 0.66 | MEN1 (0.40) | NPC1RAB9ASMN1; SMN2KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649918-B1 | Alkaline zinc-nickel alloy plating baths | ROHCO INC MCGEAN (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5417840-A | Quaternary ammonium compound containing nitrogen heterocycle, brightness | MCGEAN-ROHCO, INC. (US) | 1995-05-23 | — | — | US | disclosed |
| EP-0649918-A1 | Alkaline zinc-nickel alloy plating baths | MCGEAN-ROHCO, INC. (US) | 1995-04-26 | — | — | EP | disclosed |