Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011126 | 0.94 | NPC1 (0.47) | TSHRNPC1LMNAHPGDAKR1C1 | |
| SCHEMBL9011001 | 0.89 | TSHR (0.51) | TSHRNPC1LMNAHPGDAKR1C1 | |
| SCHEMBL9011057 | 0.83 | NPC1 (0.52) | TSHRNPC1LMNAHPGDAKR1C1 | |
| SCHEMBL7814151 | 0.82 | NPC1 (0.47) | TSHRNPC1LMNAHPGDAKR1C1 | |
| SCHEMBL9011018 | 0.82 | NPC1 (0.54) | TSHRNPC1LMNAHPGDAKR1C1 | |
| SCHEMBL7804416 | 0.81 | NPC1 (0.46) | TSHRNPC1LMNAHPGDAKR1C1 | |
| SCHEMBL7814113 | 0.80 | NPC1 (0.48) | TSHRNPC1LMNAHPGDAKR1C1 | |
| SCHEMBL9011211 | 0.79 | DRD4 (0.53) | TSHRNPC1LMNAHPGDAKR1C1 | |
| SCHEMBL9011148 | 0.79 | LMNA (0.62) | TSHRNPC1LMNAHPGDAKR1C1 | |
| SCHEMBL27302984 | 0.79 | CA12 (0.61) | TSHRNPC1LMNAHPGDAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |