Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011100 | 0.94 | LMNA (0.70) | TSHRLMNAALDH1A1USP2MAPT | |
| SCHEMBL9011170 | 0.89 | LMNA (0.70) | TSHRLMNAALDH1A1USP2MAPT | |
| SCHEMBL9011154 | 0.87 | LMNA (0.73) | TSHRLMNAALDH1A1USP2MAPT | |
| SCHEMBL7810104 | 0.85 | LMNA (0.67) | TSHRLMNAALDH1A1USP2MAPT | |
| SCHEMBL9011047 | 0.84 | ALDH1A1 (0.55) | TSHRLMNAALDH1A1USP2MAPT | |
| SCHEMBL9011005 | 0.82 | LMNA (0.73) | TSHRLMNAALDH1A1USP2MAPT | |
| SCHEMBL7814051 | 0.82 | TSHR (0.68) | TSHRLMNAALDH1A1USP2MAPT | |
| SCHEMBL9011003 | 0.81 | NPC1 (0.52) | TSHRLMNAALDH1A1NPC1DRD4 | |
| SCHEMBL9011270 | 0.81 | DRD4 (0.59) | TSHRLMNANPC1DRD4CYP1A2 | |
| SCHEMBL27298395 | 0.81 | TSHR (1.00) | TSHRLMNAALDH1A1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |