Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984506 | 0.98 | THRA (0.45) | THRATHRBSMPD1PDE3BPDE3A | |
| SCHEMBL9011621 | 0.98 | THRA (0.43) | THRATHRBSMPD1PDE3BPDE3A | |
| SCHEMBL12485109 | 0.96 | THRA (0.46) | THRATHRBSMPD1S1PR2S1PR1 | |
| SCHEMBL12483379 | 0.96 | THRA (0.46) | THRATHRBSMPD1S1PR2S1PR1 | |
| SCHEMBL8974077 | 0.90 | SMPD1 (0.49) | THRATHRBSMPD1PDE3BPDE3A | |
| SCHEMBL2038965 | 0.88 | THRA (0.47) | THRATHRBSMPD1S1PR2S1PR1 | |
| SCHEMBL2201723 | 0.88 | TLR8 (0.43) | THRBSMPD1PDE3BPDE3AMEN1 | |
| SCHEMBL339836 | 0.86 | THRA (0.49) | THRATHRBSMPD1S1PR2S1PR1 | |
| SCHEMBL197292 | 0.86 | THRA (0.49) | THRATHRBSMPD1S1PR2S1PR1 | |
| SCHEMBL2053781 | 0.86 | THRA (0.49) | THRATHRBSMPD1S1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742197-A1 | Triphenylenederivatives | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-13 | — | — | EP | disclosed |