SCHEMBL9011585

SCHEMBL9011585

CC[N+](CC)(CC)CC(C)O.O=C([O-])CCC(Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 6/20 0.36
CA1 P00915 2/20 0.33
FFAR3 O14843 2/20 0.32
HDAC3 O15379 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC8 Q9BY41 2/20 0.32
SLC22A16 Q86VW1 1/20 0.31
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2350004 0.85 BBOX1 (0.37) BBOX1CA1FFAR3HDAC3HDAC1
SCHEMBL2350553 0.79 BBOX1 (0.42) BBOX1CA1FFAR3HDAC3HDAC1
SCHEMBL2349295 0.77 BBOX1 (0.40) BBOX1CA1NFKB1
Pivalate SCHEMBL2352868 0.75 BBOX1 (0.34) BBOX1SLC22A16
Palmitic Acid SCHEMBL15402651 0.75 FABP3 (0.50) BBOX1CA1NFKB1
SCHEMBL28490712 0.74 CA1 (0.46) BBOX1CA1NFKB1
SCHEMBL2347106 0.73 BBOX1 (0.32) BBOX1SLC22A16
SCHEMBL3695430 0.72 FFAR3 (0.39) BBOX1CA1FFAR3HDAC3HDAC1
SCHEMBL27533512 0.72 FFAR3 (0.39) BBOX1CA1FFAR3HDAC3HDAC1
SCHEMBL1686206 0.72 TSHR (0.44) NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5561171-A USING A HYDROXYALKYLAMMONIUM CARBOXYLATE ALLIEDSIGNAL, INC. (US) 1996-10-01 US disclosed
US-5395859-A Metal chloroalkanoate or metal haloalkoxyacylcarboxylate trimerization catalyst ALLIEDSIGNAL INC. (US) 1995-03-07 US disclosed
EP-0590079-A1 CATALYSTS WHICH STABILIZE HYDROHALOCARBON BLOWING AGENT IN POLYISOCYANURATE FOAM FORMULATIONS DURING POLYMERIZATION AlliedSignal Inc. (US) 1994-04-06 EP disclosed
WO-1993000379-A1 CATALYSTS WHICH STABILIZE HYDROHALOCARBON BLOWING AGENT IN POLYISOCYANURATE FOAM FORMULATIONS DURING POLYMERIZATION ALLIED-SIGNAL INC. (US) 1993-01-07 WO disclosed