Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012047 | 0.83 | KDM4E (0.34) | — | |
| SCHEMBL9011954 | 0.74 | KDM4E (0.32) | — | |
| SCHEMBL9234932 | 0.73 | OPRL1 (0.33) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28929918 | 0.61 | MAPT (0.51) | — | |
| SCHEMBL15849062 | 0.59 | KMT2A (0.61) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28565276 | 0.58 | MAPT (0.41) | CYP1A2CYP2C19 | |
| SCHEMBL20912238 | 0.57 | EGLN1 (0.39) | CYP1A2CYP2C19 | |
| SCHEMBL31064098 | 0.57 | TYK2 (0.44) | — | |
| SCHEMBL20689381 | 0.57 | TYK2 (0.40) | — | |
| SCHEMBL20687662 | 0.55 | TYK2 (0.45) | CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |