Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012047 | 0.81 | KDM4E (0.34) | KDM4E | |
| SCHEMBL9234932 | 0.78 | OPRL1 (0.33) | MEN1KMT2A | |
| SCHEMBL9011926 | 0.74 | KDR (0.32) | — | |
| SCHEMBL9802855 | 0.71 | KDM4E (0.33) | KDM4E | |
| SCHEMBL15315975 | 0.63 | KDR (0.44) | KDM4E | |
| SCHEMBL9823835 | 0.59 | ALDH1A1 (0.44) | KDM4E | |
| SCHEMBL28817942 | 0.59 | KDM4E (0.43) | KDM4EMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL8698387 | 0.57 | MAPT (0.35) | MEN1KMT2A | |
| SCHEMBL9016862 | 0.57 | MAPT (0.35) | MEN1KMT2A | |
| SCHEMBL28817884 | 0.56 | KDM4E (0.40) | KDM4EMEN1KMT2APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |