Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KLK7 | P49862 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012245 | 0.98 | NAAA (0.56) | NAAACYP2C19SMN1; SMN2HPGDKLK7 | |
| SCHEMBL25252093 | 0.98 | NAAA (0.56) | NAAACYP2C19SMN1; SMN2HPGDKLK7 | |
| SCHEMBL28779449 | 0.87 | NAAA (0.44) | NAAACYP2C19SMN1; SMN2HPGDKLK7 | |
| SCHEMBL19007855 | 0.86 | NAAA (0.62) | NAAACYP2C19SMN1; SMN2HPGDHTT | |
| SCHEMBL30471400 | 0.85 | NAAA (0.45) | NAAACYP2C19SMN1; SMN2HPGDKLK7 | |
| SCHEMBL207015 | 0.84 | NAAA (0.64) | NAAACYP2C19SMN1; SMN2HPGDHTT | |
| SCHEMBL9491685 | 0.83 | NAAA (0.68) | NAAACYP2C19SMN1; SMN2HPGDHTT | |
| SCHEMBL7651380 | 0.83 | HPGD (0.47) | SMN1; SMN2HPGDKLK7MAPTMEN1 | |
| SCHEMBL7568980 | 0.82 | NAAA (0.66) | NAAACYP2C19SMN1; SMN2HPGDHTT | |
| SCHEMBL258780 | 0.82 | NAAA (0.66) | NAAACYP2C19SMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125373-A1 | METHOD FOR PREPARING RUXOLITINIB AND INTERMEDIATE THEREOF | 江苏威凯尔医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-116003503-A | Preparation method of estradiol cyclopentanepropionate | 湖北葛店人福药业有限责任公司 | 2023-04-25 | — | — | CN | disclosed |
| US-5525506-A | Process for production of avermectins and cultures therefor | PFIZER INC. (US) | 1996-06-11 | — | — | US | disclosed |
| US-5238848-A | Cultures for production of avermectins | PFIZER INC (US) | 1993-08-24 | — | — | US | disclosed |
| US-5077278-A | Parasiticides | PFIZER INC. (US) | 1991-12-31 | — | — | US | disclosed |