Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25252093 | 1.00 | NAAA (0.56) | NAAACYP2C19HPGDHTTMEN1 | |
| SCHEMBL9011955 | 0.98 | NAAA (0.55) | NAAACYP2C19HPGDHTTMEN1 | |
| SCHEMBL19007855 | 0.89 | NAAA (0.62) | NAAACYP2C19HPGDHTTCYP19A1 | |
| SCHEMBL30471400 | 0.87 | NAAA (0.45) | NAAACYP2C19HPGDHTTMEN1 | |
| SCHEMBL9491685 | 0.85 | NAAA (0.68) | NAAACYP2C19HPGDHTTMEN1 | |
| SCHEMBL28779449 | 0.85 | NAAA (0.44) | NAAACYP2C19HPGDHTTMAPT | |
| SCHEMBL7568980 | 0.85 | NAAA (0.66) | NAAACYP2C19HPGDHTTCYP19A1 | |
| SCHEMBL31069913 | 0.85 | NAAA (0.66) | NAAACYP2C19HPGDHTTCYP19A1 | |
| SCHEMBL258780 | 0.85 | NAAA (0.66) | NAAACYP2C19HPGDHTTCYP19A1 | |
| SCHEMBL9004410 | 0.83 | HPGD (0.50) | HPGDMEN1KMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525506-A | Process for production of avermectins and cultures therefor | PFIZER INC. (US) | 1996-06-11 | — | — | US | disclosed |
| US-5238848-A | Cultures for production of avermectins | PFIZER INC (US) | 1993-08-24 | — | — | US | disclosed |
| US-5077278-A | Parasiticides | PFIZER INC. (US) | 1991-12-31 | — | — | US | disclosed |