Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012047 | 0.74 | KDM4E (0.34) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL9802855 | 0.71 | KDM4E (0.33) | ALDH1A1KDM4ETSHRADRB2 | |
| SCHEMBL9012267 | 0.70 | KDM4E (0.39) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL9011975 | 0.70 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL22326 | 0.63 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL29390734 | 0.63 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL4610816 | 0.63 | GRM5 (0.71) | ALDH1A1NPSR1KCNA5GRM5CYP3A4 | |
| SCHEMBL4354346 | 0.62 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL28374591 | 0.61 | KCNA5 (0.50) | ALDH1A1HSD17B10KCNA5CYP3A4TSHR | |
| SCHEMBL9666990 | 0.60 | KDM4E (0.35) | ALDH1A1KDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |