Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012047 | 0.71 | KDM4E (0.34) | KDM4EALDH1A1HTTNPSR1TSHR | |
| SCHEMBL9012258 | 0.71 | KDM4E (0.38) | KDM4ELMNAALDH1A1GAAL3MBTL1 | |
| SCHEMBL9012001 | 0.70 | ALDH1A1 (0.37) | KDM4EALDH1A1NPSR1TSHRHSD17B10 | |
| SCHEMBL9802855 | 0.69 | KDM4E (0.33) | KDM4EALDH1A1TSHRADRB2 | |
| SCHEMBL9802864 | 0.62 | KDM4E (0.33) | KDM4ENPSR1TSHR | |
| SCHEMBL8011434 | 0.60 | KCNA5 (0.46) | KDM4EALDH1A1GAAL3MBTL1EPHX2 | |
| SCHEMBL4486176 | 0.59 | GAA (0.63) | KDM4ELMNAGAAL3MBTL1CNR1 | |
| SCHEMBL16180045 | 0.59 | GAA (0.63) | KDM4ELMNAGAAL3MBTL1CNR1 | |
| SCHEMBL14848196 | 0.59 | GAA (0.63) | KDM4ELMNAGAAL3MBTL1CNR1 | |
| SCHEMBL9666016 | 0.58 | PTK2 (0.39) | KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |