SCHEMBL9012049

SCHEMBL9012049

CCCCCC(=O)N=C(N)n1cccn1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 9/20 0.61
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011965 0.81 NOS1 (0.44) NOS1
SCHEMBL15366422 0.73 NOS1 (0.51) NOS1ELANE
SCHEMBL14936428 0.71 NOS1 (0.49) NOS1ELANE
SCHEMBL28419426 0.69 CES2 (0.48)
SCHEMBL12446838 0.68 NOS1 (0.45) NOS1ELANE
SCHEMBL16945673 0.68 NOS1 (0.45) NOS1ELANE
Hydrochloric Acid SCHEMBL28349226 0.67 CES2 (0.46)
SCHEMBL11296708 0.67 CES2 (0.50)
SCHEMBL11294421 0.67 CES2 (0.50)
SCHEMBL11288198 0.67 CES2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743320-A2 Acyl guanidine and amidine prodrugs BRISTOL-MYERS SQUIBB COMPANY (US) 1996-11-20 EP disclosed