Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 1/20 | 0.34 |
| ▸ | ATP4B | P51164 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011902 | 0.86 | AR (0.36) | TAAR1HTR1AARADRA2AADRA2C | |
| SCHEMBL8517908 | 0.86 | ADRA2A (0.33) | TAAR1HTR1AADRA2AADRA2CADRA1D | |
| SCHEMBL9011918 | 0.85 | ADRA2A (0.32) | TAAR1HTR1AADRA2AADRA2CADRA1D | |
| SCHEMBL6528639 | 0.83 | IDO1 (0.33) | TAAR1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL6483558 | 0.83 | ADRA2A (0.31) | TAAR1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL9012315 | 0.82 | BACE1 (0.42) | TAAR1ADRA2C | |
| SCHEMBL9227608 | 0.81 | TSHR (0.41) | TAAR1HTR1A | |
| SCHEMBL9012386 | 0.81 | — | — | |
| SCHEMBL6475931 | 0.81 | UTS2R (0.40) | ADRA1A | |
| SCHEMBL9012030 | 0.81 | ADRA1A (0.36) | TAAR1ADRA2AADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0354788-B1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5180836-A | Antiulcer agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0354788-A1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |