SCHEMBL901218

SCHEMBL901218

C=Cc1ccc(O)c(OC)c1.C=Cc1ccc(O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 1.00
ALDH1A1 P00352 3/20 0.67
HPGD P15428 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
TRIM24 O15164 1/20 0.67
ALDH5A1 P51649 1/20 0.67
ABAT P80404 1/20 0.67
TRIM33 Q9UPN9 1/20 0.67
TYR P14679 2/20 0.65
TTR P02766 1/20 0.62
NFE2L2 Q16236 3/20 0.61
ALOX5 P09917 4/20 0.59
CYP2D6 P10635 3/20 0.59
CYP1A2 P05177 2/20 0.59
NFKB1 P19838 2/20 0.59
HSD11B1 P28845 2/20 0.59
STAT3 P40763 2/20 0.59
NFKB2 Q00653 2/20 0.59
RELA Q04206 2/20 0.59
XDH P47989 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29452839 1.00 TRPA1 (1.00) TRPA1ALDH1A1HPGDTDP1TRIM24
SCHEMBL54199 1.00 TRPA1 (1.00) TRPA1ALDH1A1HPGDTDP1TRIM24
Methyl Alcohol SCHEMBL27907460 0.98 TRPA1 (0.96) TRPA1ALDH1A1HPGDTDP1TRIM24
SCHEMBL170629 0.93 TRPA1 (0.86) TRPA1ALDH1A1HPGDTDP1TRIM24
Ethylene Glycol SCHEMBL3792165 0.93 TRPA1 (0.86) TRPA1ALDH1A1HPGDTDP1TRIM24
Guaiacol SCHEMBL26117966 0.91 TRPA1 (0.83) TRPA1ALDH1A1HPGDTDP1TRIM24
Sulfuric Acid SCHEMBL19742909 0.91 TRPA1 (0.83) TRPA1ALDH1A1HPGDTDP1TRIM24
Phenol SCHEMBL27649594 0.90 TRPA1 (0.81) TRPA1ALDH1A1HPGDTDP1TRIM24
SCHEMBL29003595 0.88 TRPA1 (0.78) TRPA1ALDH1A1HPGDTDP1TRIM24
SCHEMBL6246403 0.87 TRPA1 (0.76) TRPA1ALDH1A1HPGDTDP1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP disclosed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO disclosed