Sulfuric Acid

Sulfuric Acid

SCHEMBL19742909

C=Cc1ccc(O)c(OC)c1.O=S(=O)(O)O

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA known ✓ P21397 1/20 0.53
MAOB known ✓ P27338 1/20 0.53
TLR9 known ✓ Q9NR96 1/20 0.53
TRPA1 O75762 1/20 0.83
ALDH1A1 P00352 3/20 0.62
HPGD P15428 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
TRIM24 O15164 1/20 0.62
ALDH5A1 P51649 1/20 0.62
ABAT P80404 1/20 0.62
TRIM33 Q9UPN9 1/20 0.62
TTR P02766 1/20 0.58
TYR P14679 2/20 0.56
ALOX5 P09917 3/20 0.55
CYP1A2 P05177 3/20 0.55
NFE2L2 Q16236 3/20 0.55
CYP2D6 P10635 3/20 0.55
NFKB1 P19838 3/20 0.55
HSD11B1 P28845 2/20 0.55
STAT3 P40763 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL11482264 0.94 TRPA1 (0.73) TRPA1ALDH1A1HPGDTDP1TRIM24
SCHEMBL54199 0.91 TRPA1 (1.00) TRPA1ALDH1A1HPGDTDP1TRIM24
SCHEMBL901218 0.91 TRPA1 (1.00) TRPA1ALDH1A1HPGDTDP1TRIM24
SCHEMBL29452839 0.91 TRPA1 (1.00) TRPA1ALDH1A1HPGDTDP1TRIM24
Methyl Alcohol SCHEMBL27907460 0.90 TRPA1 (0.96) TRPA1ALDH1A1HPGDTDP1TRIM24
Sulfuric Acid SCHEMBL18825677 0.87 ALDH1A1 (0.62) TRPA1ALDH1A1TDP1ALOX5CYP1A2
SCHEMBL170629 0.85 TRPA1 (0.86) TRPA1ALDH1A1HPGDTDP1TRIM24
Ethylene Glycol SCHEMBL3792165 0.85 TRPA1 (0.86) TRPA1ALDH1A1HPGDTDP1TRIM24
Vanillin SCHEMBL1943810 0.85 ALDH1A1 (0.86) TRPA1ALDH1A1HPGDTDP1TRIM24
Vanillin SCHEMBL28058713 0.85 ALDH1A1 (0.86) TRPA1ALDH1A1HPGDTDP1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
EP-4457513-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2024-11-06 EP claimed
CN-118435054-A Compositions and methods for diagnosing and treating chronic kidney disease 雀巢产品有限公司 2024-08-02 CN claimed
WO-2023126758-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2023-07-06 WO claimed
US-20230204604-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE SOCIETE DES PRODUITS NESTLE S.A. (CH) 2023-06-29 US claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US disclosed
US-20260034086-A1 Pet Food Compositions Comprising Caprylic Acid And Docosahexaenoic Acid And/Or Eicosapetaenoic Acid For Use In Treating Struvite Urolithiasis HILL'S PET NUTRITION, INC. (US) 2026-02-05 US disclosed
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM UNIV CALIFORNIA (US) 2025-12-11 US disclosed
US-12458617-B2 Pet food compositions comprising caprylic acid and docosahexaenoic acid and/or eicosapetaenoic acid for use in treating struvite urolithiasis HILL'S PET NUTRITION, INC. (US) 2025-11-04 US disclosed
US-20240424137-A1 Biomarkers For Lysosomal Storage Diseases AMICUS THERAPEUTICS, INC. (US) 2024-12-26 US disclosed
EP-4457513-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2024-11-06 EP disclosed
EP-4413376-A1 BIOMARKERS FOR LYSOSOMAL STORAGE DISEASES Amicus Therapeutics, Inc. (US) 2024-08-14 EP disclosed
US-20240257973-A1 DISEASE SPECTRUM CLASSIFICATION PATIENTSLIKEME LLC (US) 2024-08-01 US disclosed
US-11894139-B1 Disease spectrum classification PATIENTSLIKEME LLC (US) 2024-02-06 US disclosed
WO-2023126758-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2023-07-06 WO disclosed
US-20230204604-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE SOCIETE DES PRODUITS NESTLE S.A. (CH) 2023-06-29 US disclosed
WO-2023060233-A1 BIOMARKERS FOR LYSOSOMAL STORAGE DISEASES AMICUS THERAPEUTICS, INC. (US) 2023-04-13 WO disclosed
US-20220202759-A1 Pet Food Compositions Comprising Caprylic Acid and Docosahexaenoic Acid and/or Eicosapetaenoic Acid for Use in Treating Struvite Urolithiasis HILL'S PET NUTRITION, INC. (US) 2022-06-30 US disclosed
US-20220102000-A1 PREDICTING BLOOD METABOLITES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-03-31 US disclosed
US-20170370954-A1 Biomarkers for Fatty Liver Disease and Methods Using the Same METABOLON, INC. 2017-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM CYP27A1, LIPC, CYP46A1 MAOA 2319/4885MAOB 1810/4885TLR9 3593/4885
US-20260034086-A1 Pet Food Compositions Comprising Caprylic Acid And Docosahexaenoic Acid And/Or Eicosapetaenoic Acid For Use In Treating Struvite Urolithiasis FPR2, FPR1, FPR3 MAOA 2258/4885MAOB 3013/4885TLR9 1082/4885
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 MAOA 1233/4885MAOB 1784/4885TLR9 2040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.