Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TXN | P10599 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012490 | 0.85 | TSHR (0.39) | TAAR1HDAC1TXNTXNRD1FDPS | |
| SCHEMBL9012538 | 0.81 | HDAC1 (0.42) | TAAR1HDAC1TXNTXNRD1FDPS | |
| SCHEMBL9360886 | 0.81 | TAAR1 (0.39) | TAAR1HDAC1FDPSBRD4CYP1A2 | |
| SCHEMBL9012172 | 0.81 | TAAR1 (0.35) | TAAR1HDAC1TXNTXNRD1FDPS | |
| SCHEMBL9012295 | 0.76 | TXN (0.35) | HDAC1TXNTXNRD1FDPSKDM6B | |
| SCHEMBL9011963 | 0.74 | TAAR1 (0.39) | TAAR1BRD4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9012424 | 0.71 | ADRA2A (0.42) | FDPSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9012434 | 0.71 | SMN1; SMN2 (0.40) | HDAC1TXNTXNRD1FDPSLMNA | |
| SCHEMBL9012305 | 0.71 | HDAC1 (0.40) | HDAC1TXNTXNRD1FDPSALDH1A1 | |
| SCHEMBL4765782 | 0.69 | HPGD (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0354788-B1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-5180836-A | Antiulcer agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0354788-A1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |