Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012048 | 0.81 | HPGD (0.51) | HPGDLMNAMEN1KMT2ATSHR | |
| SCHEMBL6481930 | 0.80 | HPGD (0.51) | HPGDLMNAMEN1KMT2ATSHR | |
| SCHEMBL9012520 | 0.75 | HPGD (0.47) | HPGDLMNAMEN1KMT2ATSHR | |
| SCHEMBL6483534 | 0.74 | RAB9A (0.64) | HPGDLMNAMEN1KMT2ATSHR | |
| SCHEMBL10478356 | 0.73 | SMN1; SMN2 (0.47) | HPGDLMNAMEN1KMT2ATSHR | |
| SCHEMBL9012107 | 0.73 | ACHE (0.35) | HPGDGAAL3MBTL1ACHE | |
| SCHEMBL9678318 | 0.71 | SMN1; SMN2 (0.47) | HPGDLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL9838119 | 0.71 | POLB (0.67) | HPGDLMNAMEN1KMT2ATSHR | |
| SCHEMBL9677090 | 0.70 | HRH4 (0.55) | HPGDLMNAMEN1KMT2ATSHR | |
| SCHEMBL9695295 | 0.70 | TP53 (0.67) | HPGDLMNAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0354788-B1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-5180836-A | Antiulcer agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0354788-A1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |