Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589006 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL9012631 | 0.93 | ALDH1A1 (0.41) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL62195 | 0.88 | ALDH1A1 (0.62) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL9012463 | 0.85 | PKM (0.51) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL9591081 | 0.85 | PKM (0.51) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL13294304 | 0.85 | ALDH1A1 (0.59) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL2969474 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL15344215 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL17212248 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL27034976 | 0.84 | PRSS1 (0.57) | ALDH1A1CYP3A4LMNAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517104-B1 | 1,3,5-Triazine derivatives, their preparation and use as sunscreens | 3V SIGMA SPA (IT) | 1996-11-27 | — | — | EP | claimed |
| EP-0517104-A1 | 1,3,5-Triazine derivatives, their preparation and use as sunscreens | 3V SIGMA S.p.A (IT) | 1992-12-09 | — | — | EP | claimed |