Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 14/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
| ▸ | CCR1 | P32246 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 2/20 | 0.54 |
| ▸ | CCR8 | P51685 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29193811 | 0.90 | GRM5 (0.56) | GRM5KDM4ELMNAMETAP1CCR1 | |
| SCHEMBL9792784 | 0.88 | NPY5R (0.45) | GRM5METAP1CCR1CCR5CCR8 | |
| SCHEMBL29500425 | 0.88 | NPY5R (0.45) | GRM5METAP1CCR1CCR5CCR8 | |
| SCHEMBL31463173 | 0.81 | KDM4E (0.54) | GRM5KDM4ELMNAMETAP1CCR1 | |
| SCHEMBL7964599 | 0.81 | KDM4E (0.54) | GRM5KDM4ELMNAMETAP1CCR1 | |
| SCHEMBL2949191 | 0.81 | ASIC3 (0.53) | GRM5LMNACYP1A2ALDH1A1TSHR | |
| SCHEMBL30158989 | 0.81 | ASIC3 (0.53) | GRM5LMNACYP1A2ALDH1A1TSHR | |
| SCHEMBL20761979 | 0.80 | GRM5 (0.48) | GRM5KDM4EMETAP1METAP2HTT | |
| SCHEMBL17115942 | 0.79 | GRM5 (0.41) | GRM5KDM4EMETAP1METAP2HTT | |
| SCHEMBL17116755 | 0.79 | GRM5 (0.48) | GRM5KDM4ELMNAMETAP1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167144-A1 | PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION | Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) | 2023-06-01 | — | — | US | claimed |
| CN-111518145-A | Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof | 荆楚理工学院 | 2020-08-11 | — | — | CN | claimed |
| CN-104755477-B | 2-aminopyridine compounds | 默克专利股份公司 | 2017-09-26 | — | — | CN | claimed |
| CN-117343002-A | Synthesis method of beta-cyanoalkyl pyridine compound | 西南医科大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-111518145-B | Cyano-bridged metal organic compound with intramolecular magnetic transformation and preparation method and application thereof | 荆楚理工学院 | 2023-06-20 | — | — | CN | disclosed |
| US-20230167144-A1 | PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION | Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) | 2023-06-01 | — | — | US | disclosed |
| CN-111518145-A | Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof | 荆楚理工学院 | 2020-08-11 | — | — | CN | disclosed |
| CN-106458992-B | Pyridyl piperidine | 默克专利股份公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-108513574-A | N-sulfonylated pyrazolo [3,4-b ] pyridine-6-carboxamides and methods of use | 艾伯维公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-108431002-A | Substituted pyrazolo [3, 4-b ] pyridine-6-carboxylic acids and uses thereof | 艾伯维公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-104755477-B | 2-aminopyridine compounds | 默克专利股份公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-104684899-B | Substituted sulfonamide compounds | 霍夫曼-拉罗奇有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-106458992-A | Pyridyl piperidines | 默克专利股份公司 | 2017-02-22 | — | — | CN | disclosed |
| US-20160351825-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | DOOSAN CORPORATION (KR) | 2016-12-01 | — | — | US | disclosed |
| EP-2203439-A1 | 1',3'-DISUBSTITUTED-4-PHENYL-3,4,5,6-TETRAHYDRO-2H, 1'H-Ý1, 4'¨BIPYRIDINYL-2'-ONES | Ortho-McNeil-Janssen Pharmaceuticals, Inc. (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009033704-A1 | 1',3'-DISUBSTITUTED-4-PHENYL-3,4,5,6-TETRAHYDRO-2H, 1'H-[1, 4'] BIPYRIDINYL-2'-ONES | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160351825-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | OR10J3, ORAI2, ETV6 | GRM5 2470/4885KDM4E 1209/4885LMNA 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.