Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 17/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590366 | 1.00 | IDH1 (0.56) | IDH1ALDH1A1LMNACYP3A4CYP1A2 | |
| SCHEMBL9012418 | 0.97 | LMNA (0.53) | IDH1ALDH1A1LMNACYP3A4CYP1A2 | |
| SCHEMBL6910054 | 0.83 | LMNA (0.68) | IDH1ALDH1A1LMNACYP3A4CYP1A2 | |
| SCHEMBL6910053 | 0.83 | LMNA (0.68) | IDH1ALDH1A1LMNACYP3A4CYP1A2 | |
| SCHEMBL6910050 | 0.83 | LMNA (0.68) | IDH1ALDH1A1LMNACYP3A4CYP1A2 | |
| SCHEMBL6909186 | 0.83 | LMNA (0.68) | IDH1ALDH1A1LMNACYP3A4CYP1A2 | |
| SCHEMBL6909183 | 0.83 | LMNA (0.68) | IDH1ALDH1A1LMNACYP3A4CYP1A2 | |
| SCHEMBL3221159 | 0.80 | LMNA (0.47) | IDH1ALDH1A1LMNACYP3A4CYP1A2 | |
| SCHEMBL13894203 | 0.77 | LMNA (0.71) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL13227847 | 0.76 | KMT2A (0.78) | ALDH1A1KDM4EMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517104-B1 | 1,3,5-Triazine derivatives, their preparation and use as sunscreens | 3V SIGMA SPA (IT) | 1996-11-27 | — | — | EP | claimed |
| EP-0517104-A1 | 1,3,5-Triazine derivatives, their preparation and use as sunscreens | 3V SIGMA S.p.A (IT) | 1992-12-09 | — | — | EP | claimed |