SCHEMBL9012772

SCHEMBL9012772

CCN(CC)c1ccc(C(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
TSHR P16473 2/20 0.44
CNR2 P34972 8/20 0.43
GFER P55789 2/20 0.42
PSMD14 O00487 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
RECQL P46063 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
NR1H2 P55055 4/20 0.40
NR1H3 Q13133 4/20 0.40
ALDH3A1 P30838 1/20 0.40
ALDH1A3 P47895 1/20 0.40
GRK6 P43250 1/20 0.39
TERT O14746 1/20 0.38
S100B P04271 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013403 0.79 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL22159396 0.78 ESR1 (0.38)
SCHEMBL28507546 0.72 CHRNA7 (0.38) ALDH1A1TSHRTDP1KDM4EMEN1
SCHEMBL131813 0.72 ALDH1A1 (0.56) ALDH1A1TSHRCNR2GFERPSMD14
SCHEMBL1735497 0.71 ALDH1A1 (0.74) ALDH1A1TSHRCNR2GFERPSMD14
SCHEMBL28914917 0.70 ALDH1A1 (0.50) ALDH1A1TSHRCNR2GFERPSMD14
SCHEMBL12000833 0.70 ALDH1A1 (0.54) ALDH1A1TSHRCNR2GFERPSMD14
SCHEMBL10080950 0.70 ALDH1A1 (0.60) ALDH1A1TSHRCNR2GFERPSMD14
SCHEMBL4434581 0.70 ALDH1A1 (0.54) ALDH1A1TSHRCNR2GFERPSMD14
SCHEMBL10578908 0.70 IDO1 (0.38) TSHRMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed