Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22159396 | 0.82 | ESR1 (0.38) | — | |
| SCHEMBL9012772 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRL3MBTL1CYP3A4MAPK1 | |
| SCHEMBL28507546 | 0.77 | CHRNA7 (0.38) | ALDH1A1TSHRTDP1MAPTKMT2A | |
| SCHEMBL10578908 | 0.74 | IDO1 (0.38) | TSHRMAPK1CYP1A2ATM | |
| SCHEMBL23391009 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15HSD17B10SLC2A1 | |
| SCHEMBL320072 | 0.72 | ESR1 (0.54) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL6516945 | 0.72 | CYP2A6 (0.36) | CYP1A2 | |
| SCHEMBL10821953 | 0.72 | ESR1 (0.32) | — | |
| SCHEMBL323076 | 0.72 | ALDH1A1 (0.37) | ALDH1A1TSHRGAACYP3A4TDP1 | |
| SCHEMBL8462292 | 0.72 | ESR1 (0.54) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5558700-A | QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR | THE PILOT INK CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |