Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3017723 | 0.98 | KEAP1 (0.42) | KEAP1NFE2L2ALDH1A1TSHREPHX1 | |
| SCHEMBL3017727 | 0.98 | KEAP1 (0.42) | KEAP1NFE2L2ALDH1A1TSHREPHX1 | |
| SCHEMBL28730098 | 0.95 | KEAP1 (0.44) | KEAP1NFE2L2ALDH1A1TSHREPHX1 | |
| SCHEMBL5981455 | 0.86 | ALDH1A1 (0.44) | KEAP1NFE2L2ALDH1A1EPHX1PDK1 | |
| SCHEMBL18483080 | 0.85 | — | — | |
| Acetamide SCHEMBL28432259 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRCES2 | |
| SCHEMBL20472266 | 0.77 | EPHX1 (0.37) | KEAP1NFE2L2ALDH1A1EPHX1PDK1 | |
| SCHEMBL29416278 | 0.77 | EPHX1 (0.37) | KEAP1NFE2L2ALDH1A1EPHX1PDK1 | |
| SCHEMBL14473686 | 0.76 | EPHX1 (0.39) | KEAP1NFE2L2ALDH1A1TSHREPHX1 | |
| SCHEMBL1876976 | 0.76 | EPHX1 (0.39) | KEAP1NFE2L2ALDH1A1TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5520725-A | Dental glass ionomer cement composition | GC CORPORATION (JP) | 1996-05-28 | — | — | US | claimed |
| US-5520725-A | Dental glass ionomer cement composition | GC CORPORATION (JP) | 1996-05-28 | — | — | US | disclosed |