SCHEMBL9013063

SCHEMBL9013063

NC(=O)C1C2C=CC(O2)C1C(=O)Nc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.59
HPGD P15428 2/20 0.59
GLA P06280 1/20 0.59
PKM P14618 1/20 0.59
HSD17B10 Q99714 1/20 0.59
PPM1B O75688 4/20 0.58
F13A1 P00488 2/20 0.58
TGM2 P21980 2/20 0.58
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
KDM4E B2RXH2 1/20 0.49
MAPT P10636 1/20 0.48
POLB P06746 1/20 0.47
HTT P42858 1/20 0.47
USP2 O75604 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18495273 0.77 MEN1 (0.60) ALDH1A1HPGDGLAPKMHSD17B10
SCHEMBL9974830 0.77 MEN1 (0.60) ALDH1A1HPGDGLAPKMHSD17B10
SCHEMBL9013304 0.75 PPM1B (0.39) ALDH1A1HSD17B10PPM1BMEN1KMT2A
SCHEMBL9013080 0.75 POLB (0.58) ALDH1A1HPGDF13A1TGM2MEN1
SCHEMBL2873702 0.74 PPM1B (0.38) ALDH1A1HSD17B10PPM1BMEN1KMT2A
SCHEMBL728769 0.74 PPM1B (0.74) ALDH1A1HPGDGLAPKMHSD17B10
SCHEMBL727169 0.74 PPM1B (0.74) ALDH1A1HPGDGLAPKMHSD17B10
SCHEMBL9013023 0.73 PPM1B (0.42) ALDH1A1HSD17B10PPM1BMEN1KMT2A
SCHEMBL12040442 0.73 ALDH1A1 (0.70) ALDH1A1HPGDGLAPKMHSD17B10
SCHEMBL13002242 0.72 PPM1B (0.52) ALDH1A1HSD17B10PPM1BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0577002-B1 Poly(methacryl imides) with elevated heat distortion resistance BASF AG (DE) 1996-12-04 EP disclosed
US-5354814-A Molding materials; heat resistance BASF AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
EP-0577002-A1 Poly(methacryl imides) with elevated heat distortion resistance BASF Aktiengesellschaft (DE) 1994-01-05 EP disclosed