Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013269 | 0.92 | MEN1 (0.52) | MEN1KMT2ATDP1ALOX5DRD2 | |
| SCHEMBL9013604 | 0.85 | MEN1 (0.52) | MEN1KMT2ATDP1ALOX5 | |
| Hydrochloric Acid SCHEMBL9013747 | 0.81 | ESR1 (0.52) | — | |
| SCHEMBL9013352 | 0.80 | MEN1 (0.52) | MEN1KMT2ATDP1ALOX5ALDH1A1 | |
| SCHEMBL9013406 | 0.76 | — | — | |
| SCHEMBL9013417 | 0.76 | ESR1 (0.46) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL9013741 | 0.74 | MEN1 (0.50) | MEN1KMT2ATDP1ALOX5DRD2 | |
| Hydrochloric Acid SCHEMBL6592530 | 0.73 | SLC6A2 (0.52) | DRD2DRD4DRD3ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6586905 | 0.72 | DRD2 (0.56) | DRD2DRD4DRD3ALDH1A1LMNA | |
| SCHEMBL9013419 | 0.72 | ESR1 (0.45) | MEN1KMT2AALOX5DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |