Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013419 | 0.92 | ESR1 (0.45) | MEN1KMT2AESR1ALOX5ALDH1A1 | |
| SCHEMBL9013654 | 0.92 | KMT2A (0.50) | MEN1KMT2ATDP1ALOX5ALDH1A1 | |
| SCHEMBL9013760 | 0.90 | CYP2D6 (0.48) | MEN1KMT2ATDP1CACNA1ACACNA2D1 | |
| SCHEMBL9013334 | 0.90 | KMT2A (0.49) | MEN1KMT2ATDP1ALOX5ALDH1A1 | |
| SCHEMBL9013604 | 0.88 | MEN1 (0.52) | MEN1KMT2ATDP1ESR1ALOX5 | |
| SCHEMBL9013385 | 0.86 | MEN1 (0.47) | MEN1KMT2ATDP1 | |
| SCHEMBL9013689 | 0.85 | ACHE (0.47) | MEN1KMT2ATDP1ALOX5 | |
| SCHEMBL9013518 | 0.83 | CYP2D6 (0.46) | MEN1KMT2AALOX5 | |
| SCHEMBL9013570 | 0.81 | ACHE (0.44) | MEN1KMT2AALOX5 | |
| SCHEMBL9013417 | 0.81 | ESR1 (0.46) | MEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |