Toluene

Toluene

SCHEMBL9013272

CN(C)CCN(C)C.Cc1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
LMNA P02545 2/20 0.61
ALOX12 P18054 1/20 0.61
ACHE P22303 1/20 0.61
TAAR1 Q96RJ0 1/20 0.54
HTR2A P28223 3/20 0.50
HRH1 P35367 3/20 0.50
MEN1 O00255 1/20 0.46
TNNI3 P19429 1/20 0.46
TNNT2 P45379 1/20 0.46
TNNC1 P63316 1/20 0.46
KMT2A Q03164 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.45
CYP2D6 P10635 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP2C19 P33261 1/20 0.43
CYP1A2 P05177 1/20 0.43
CHRM2 P08172 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL9516032 0.85 TSHR (0.50) TSHRLMNAALOX12ACHETAAR1
Toluene SCHEMBL16465853 0.84 HTR2A (0.48) TSHRLMNAALOX12ACHETAAR1
Toluene SCHEMBL3958941 0.82 ACHE (0.79) TSHRLMNAALOX12ACHEHTR2A
Toluene SCHEMBL27670735 0.79 ACHE (0.73) TSHRLMNAALOX12ACHEHTR2A
Toluene SCHEMBL28245344 0.79 ACHE (0.73) TSHRLMNAALOX12ACHEHTR2A
Toluene SCHEMBL28070600 0.79 ACHE (0.73) TSHRLMNAALOX12ACHEMEN1
Toluene SCHEMBL18037047 0.79 ACHE (0.73) TSHRLMNAALOX12ACHEHTR2A
Toluene SCHEMBL27984465 0.79 ACHE (0.73) TSHRLMNAALOX12ACHEMEN1
Toluene SCHEMBL28783234 0.79 ACHE (0.73) TSHRLMNAALOX12ACHEHTR2A
Toluene SCHEMBL27499167 0.79 ACHE (0.73) TSHRLMNAALOX12ACHEHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210569-A1 NOVEL COMPOUND, CONJUGATED POLYMER AND METHOD FOR PRODUCING SAME, FILM FORMATION COMPOSITION, ORGANIC THIN FILM, AND ORGANIC SEMICONDUCTOR ELEMENT 東ソー株式会社 2023-11-02 WO disclosed
US-5556997-A Enhanced synthesis of racemic metallocenes ALBEMARLE CORPORATION (US) 1996-09-17 US disclosed