Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL9013272 | 0.85 | TSHR (0.61) | TSHRLMNAALOX12ACHETAAR1 | |
| O-Xylene SCHEMBL27833269 | 0.84 | TSHR (0.48) | TSHRLMNAACHETAAR1HTR2A | |
| Toluene SCHEMBL2063451 | 0.80 | ACHE (0.69) | TSHRLMNAALOX12ACHEMAPT | |
| SCHEMBL9549561 | 0.78 | CYP3A4 (0.50) | TSHRLMNATAAR1HTR2AHRH1 | |
| Toluene SCHEMBL28269304 | 0.78 | ACHE (0.65) | TSHRLMNAALOX12ACHETAAR1 | |
| Toluene SCHEMBL330032 | 0.77 | ACHE (0.73) | TSHRLMNAALOX12ACHETAAR1 | |
| Toluene SCHEMBL5595092 | 0.77 | ACHE (0.73) | TSHRLMNAALOX12ACHETAAR1 | |
| Toluene SCHEMBL11448382 | 0.77 | ACHE (0.73) | TSHRLMNAALOX12ACHETAAR1 | |
| Toluene SCHEMBL16465853 | 0.76 | HTR2A (0.48) | TSHRLMNAALOX12ACHETAAR1 | |
| Toluene SCHEMBL11862000 | 0.75 | LMNA (0.61) | TSHRLMNAALOX12ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056685-A | Method for synthesizing doxylamine succinate | 珠海市海瑞德生物科技有限公司 | 2017-08-18 | — | — | CN | claimed |
| CN-110498764-B | Synthesis method of doxylamine succinate | 深圳沃兰德药业有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-110498764-A | A kind of synthetic method of doxylamine succinate | SHENZHEN ORIENTAL PHARMACEUTICAL CO LTD | 2019-11-26 | — | — | CN | disclosed |
| CN-107056685-A | Method for synthesizing doxylamine succinate | 珠海市海瑞德生物科技有限公司 | 2017-08-18 | — | — | CN | disclosed |
| EP-0229329-B1 | BENZAZEPINE DERIVATIVES | E.R. Squibb & Sons, Inc. (US) | 1993-07-28 | — | — | EP | disclosed |
| US-4752645-A | Benzazepine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1988-06-21 | — | — | US | disclosed |
| EP-0229329-A1 | Benzazepine derivatives | E.R. Squibb & Sons, Inc. (US) | 1987-07-22 | — | — | EP | disclosed |