Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573086 | 0.86 | THRB (0.52) | LSSHTTESR1ESR2GAA | |
| SCHEMBL7579498 | 0.86 | THRB (0.52) | LSSHTTESR1ESR2GAA | |
| SCHEMBL7573889 | 0.86 | THRB (0.52) | LSSHTTESR1ESR2GAA | |
| SCHEMBL7581397 | 0.86 | THRB (0.52) | LSSHTTESR1ESR2GAA | |
| SCHEMBL7573281 | 0.86 | THRB (0.52) | LSSHTTESR1ESR2GAA | |
| SCHEMBL7573088 | 0.86 | THRB (0.52) | LSSHTTESR1ESR2GAA | |
| SCHEMBL7573309 | 0.86 | THRB (0.52) | LSSHTTESR1ESR2GAA | |
| SCHEMBL7575091 | 0.86 | THRB (0.52) | LSSHTTESR1ESR2GAA | |
| SCHEMBL7572221 | 0.85 | ESR1 (0.42) | PPARALSSHTTESR1ESR2 | |
| SCHEMBL7579545 | 0.85 | ESR1 (0.42) | PPARALSSHTTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8245520-A | — | — | None | — | — | JP | disclosed |
| JP-H08245520-A | PHOTOCROSS-LINKABLE NAPHTHALENE DERIVATIVE | F HOFFMANN LA ROCHE AG | 1996-09-24 | — | — | JP | disclosed |