SCHEMBL901332

SCHEMBL901332

CC(C)CCOC(=O)CC(C)C.CC(C)CCOC(=O)CC(C)C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.49
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
TDP1 Q9NUW8 2/20 0.43
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP3 P08254 1/20 0.42
MMP9 P14780 1/20 0.42
MMP13 P45452 1/20 0.42
ALDH1A1 P00352 3/20 0.40
MAPK1 P28482 2/20 0.40
PKM P14618 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 1/20 0.39
EPHX2 P34913 1/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113763 1.00 CYP19A1 (0.49) CYP19A1CA12CA1CA2CA9
3-Methylbutanoic Acid SCHEMBL5033115 0.92 CYP19A1 (0.44) CYP19A1CA12CA1CA2CA9
SCHEMBL23036805 0.88 ALOX15 (0.44) CYP19A1CA2TDP1MMP1MMP2
SCHEMBL5033117 0.88 CYP19A1 (0.41) CYP19A1CA12CA1CA2CA9
SCHEMBL18378814 0.87 MMP1 (0.46) CA2TDP1MMP1MMP2MMP3
SCHEMBL5907632 0.86 CYP19A1 (0.50) CYP19A1CA12CA1CA2CA9
SCHEMBL10510712 0.86 CYP19A1 (0.42) CYP19A1CA2TDP1MMP1MMP2
SCHEMBL25445590 0.86 CYP19A1 (0.50) CYP19A1CA12CA1CA2CA9
SCHEMBL18338892 0.86 MMP1 (0.39) CYP19A1TDP1MMP1MMP2MMP3
SCHEMBL11090796 0.85 CYP19A1 (0.45) CYP19A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP disclosed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO disclosed