SCHEMBL9013393

SCHEMBL9013393

CCCCCC1(CCCCC2CCC(c3cc(F)c(F)c(F)c3)CC2)CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
OPRL1 P41146 4/20 0.34
CYP1A2 P05177 1/20 0.33
BACE1 P56817 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C8 P10632 1/20 0.30
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8456817 0.96 OPRL1 (0.34) MEN1KMT2AOPRL1CYP1A2BACE1
SCHEMBL9014291 0.90 MEN1 (0.33) MEN1KMT2AOPRL1CYP1A2BACE1
SCHEMBL9013211 0.88 OPRL1 (0.35) MEN1KMT2AOPRL1CYP1A2GAA
SCHEMBL9506590 0.86 MEN1 (0.40) MEN1KMT2ACYP1A2GAAMAPT
SCHEMBL9506596 0.86 MEN1 (0.40) MEN1KMT2ACYP1A2GAAMAPT
SCHEMBL9013258 0.85 OPRL1 (0.35) MEN1KMT2AOPRL1MAPTCYP3A4
SCHEMBL9013693 0.85 OPRL1 (0.33) MEN1KMT2AOPRL1GAAMAPT
SCHEMBL9013621 0.85 KDM1A (0.36) MEN1KMT2AOPRL1CYP3A4CYP2C8
SCHEMBL9763556 0.85 MAPT (0.40) MEN1KMT2ACYP1A2GAAMAPT
SCHEMBL7511813 0.85 MEN1 (0.39) MEN1KMT2ACYP1A2GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 EP disclosed
US-5468421-A Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1995-11-21 US disclosed
EP-0568040-A1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1993-11-03 EP disclosed