Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013211 | 0.90 | OPRL1 (0.35) | OPRL1CYP3A4CYP2C8S1PR3S1PR1 | |
| SCHEMBL872280 | 0.88 | CYP2C9 (0.39) | CYP3A4CYP2C8S1PR3S1PR1SGPL1 | |
| SCHEMBL872279 | 0.88 | CYP2C9 (0.39) | CYP3A4CYP2C8S1PR3S1PR1SGPL1 | |
| SCHEMBL9013258 | 0.87 | OPRL1 (0.35) | OPRL1CYP3A4CYP2C8S1PR3S1PR1 | |
| SCHEMBL2868886 | 0.86 | SPHK1 (0.39) | CYP3A4CYP2C8S1PR3MEN1KMT2A | |
| SCHEMBL9013621 | 0.86 | KDM1A (0.36) | OPRL1CYP3A4CYP2C8S1PR3S1PR1 | |
| SCHEMBL9013393 | 0.85 | MEN1 (0.34) | OPRL1CYP3A4CYP2C8S1PR3MEN1 | |
| SCHEMBL9013605 | 0.83 | CYP2C9 (0.35) | OPRL1CYP3A4CYP2C8S1PR3S1PR1 | |
| SCHEMBL9013289 | 0.83 | CYP2C9 (0.42) | OPRL1CYP3A4CYP2C8S1PR3S1PR1 | |
| SCHEMBL9013349 | 0.83 | CTSK (0.35) | OPRL1CYP3A4CYP2C8S1PR3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568040-B1 | Cyclohexane derivative and liquid crystal composition containing the same | CHISSO CORP (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5468421-A | Cyclohexane derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |
| EP-0568040-A1 | Cyclohexane derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1993-11-03 | — | — | EP | disclosed |