Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012137 | 0.87 | KDM4E (0.34) | TAAR1ADRA2AADRA2BADRA2CHRH4 | |
| SCHEMBL9012063 | 0.83 | POLB (0.33) | TAAR1HRH4 | |
| SCHEMBL17368397 | 0.71 | ALDH1A1 (0.38) | TAAR1NISCH | |
| SCHEMBL4685300 | 0.70 | ALDH1A1 (0.37) | TAAR1 | |
| SCHEMBL5240039 | 0.69 | ADRA2A (0.44) | TAAR1MTORADKNISCHADRA2A | |
| SCHEMBL4685296 | 0.69 | ALDH1A1 (0.35) | TAAR1 | |
| SCHEMBL30864379 | 0.65 | MTOR (0.42) | TAAR1MTORADKNISCHADRA2A | |
| SCHEMBL17007042 | 0.65 | SLC6A2 (0.35) | ADRA2AADRA2B | |
| SCHEMBL9011918 | 0.64 | ADRA2A (0.32) | TAAR1MTORADKNISCHADRA2A | |
| SCHEMBL698729 | 0.62 | ADRA2A (0.60) | TAAR1MTORADKNISCHADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5180836-A | Antiulcer agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |