Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 15/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | GBA1 | P04062 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | LTK | P29376 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | CLK2 | P49760 | 1/20 | 0.59 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223997 | 0.88 | ABCG2 (0.62) | ABCG2MEN1NPC1GBA1RAB9A | |
| SCHEMBL12963169 | 0.85 | NPC1 (0.59) | ABCG2MEN1NPC1GBA1RAB9A | |
| SCHEMBL11516034 | 0.84 | ABCG2 (0.58) | ABCG2MEN1NPC1GBA1RAB9A | |
| SCHEMBL7522515 | 0.84 | ABCG2 (0.68) | ABCG2MEN1NPC1GBA1RAB9A | |
| SCHEMBL24227649 | 0.83 | ADORA1 (0.63) | ABCG2MEN1KMT2ALMNAABCB1 | |
| SCHEMBL387105 | 0.82 | SMN1; SMN2 (0.73) | ABCG2MEN1NPC1GBA1RAB9A | |
| SCHEMBL21977560 | 0.82 | ABCG2 (1.00) | ABCG2MEN1NPC1GBA1RAB9A | |
| SCHEMBL13823658 | 0.82 | NPC1 (0.51) | ABCG2MEN1NPC1GBA1RAB9A | |
| SCHEMBL7913550 | 0.82 | LMNA (0.73) | ABCG2MEN1NPC1GBA1RAB9A | |
| SCHEMBL390297 | 0.82 | ABCG2 (0.62) | ABCG2MEN1NPC1GBA1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321735-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2016-04-26 | — | — | US | disclosed |
| US-8785630-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-06-13 | — | — | US | disclosed |
| US-8389718-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2012-01-26 | — | — | US | disclosed |
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |
| CN-1059908-A | Pyrimidine derivatives and medicine thereof | NIPPON SHINYAKU CO LTD (JP) | 1992-04-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | ABCG2 1604/4885MEN1 4237/4885NPC1 4257/4885 |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | ABCG2 1604/4885MEN1 4237/4885NPC1 4257/4885 |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | ABCG2 1604/4885MEN1 4237/4885NPC1 4257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.