Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237986 | 0.87 | EGFR (0.60) | DYRK1ANPC1RAB9AKDM4EMAPT | |
| SCHEMBL7375465 | 0.84 | DYRK1A (0.51) | DYRK1ANPC1RAB9AKDM4EMAPT | |
| SCHEMBL3304247 | 0.83 | MAPT (0.53) | DYRK1ANPC1RAB9AKDM4EMAPT | |
| SCHEMBL25841681 | 0.83 | NPC1 (0.59) | DYRK1ANPC1RAB9AKDM4EMAPT | |
| SCHEMBL10967059 | 0.82 | MAPT (0.46) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL3453296 | 0.81 | DYRK1A (0.71) | DYRK1ANPC1RAB9AKDM4EMAPT | |
| SCHEMBL11247361 | 0.80 | NPC1 (0.64) | DYRK1ANPC1RAB9AKDM4EMAPT | |
| SCHEMBL9013572 | 0.79 | KDM4E (0.53) | DYRK1ANPC1RAB9AKDM4EMAPT | |
| SCHEMBL5420904 | 0.79 | ADORA3 (0.43) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL4297486 | 0.78 | KMT2A (0.51) | RAB9AKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |