Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237986 | 0.87 | EGFR (0.60) | KDM4EDYRK1ANPC1RAB9ACXCL12 | |
| SCHEMBL3451541 | 0.84 | KDM4E (0.67) | KDM4EDYRK1ANPC1RAB9AMEN1 | |
| SCHEMBL4748830 | 0.82 | MAPT (0.55) | KDM4ECXCL12MEN1KMT2AMAOA | |
| SCHEMBL1644753 | 0.81 | DYRK1A (0.71) | KDM4EDYRK1ANPC1RAB9AEGFR | |
| SCHEMBL26967691 | 0.81 | KDM4E (0.54) | KDM4EDYRK1ANPC1RAB9AMEN1 | |
| SCHEMBL10686590 | 0.80 | MEN1 (0.57) | KDM4ENPC1RAB9ACXCL12MEN1 | |
| SCHEMBL25841681 | 0.79 | NPC1 (0.59) | KDM4EDYRK1ANPC1RAB9AMEN1 | |
| SCHEMBL9013563 | 0.79 | DYRK1A (0.50) | KDM4EDYRK1ANPC1RAB9ACXCL12 | |
| SCHEMBL25068057 | 0.79 | KDM4E (0.58) | KDM4ERAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL600729 | 0.79 | RAD51 (0.44) | KDM4ECXCL12MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |