SCHEMBL9013605

SCHEMBL9013605

CCCCCC1(CCCCC2CCC(c3ccc(C(=O)Cl)c(F)c3)CC2)CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
OPRL1 P41146 7/20 0.34
CNR2 P34972 1/20 0.34
S1PR1 P21453 5/20 0.33
SGPL1 O95470 1/20 0.33
S1PR4 O95977 1/20 0.33
S1PR5 Q9H228 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C8 P10632 1/20 0.33
S1PR3 Q99500 1/20 0.33
TP53 P04637 2/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013289 0.90 CYP2C9 (0.42) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL9669086 0.89 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAS1PR1
SCHEMBL9013211 0.86 OPRL1 (0.35) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL9013292 0.84 CYP2C9 (0.47) CYP2C9MAPTALDH1A1LMNACNR2
SCHEMBL9013258 0.83 OPRL1 (0.35) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL9013693 0.83 OPRL1 (0.33) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL9013621 0.82 KDM1A (0.36) CYP2C9OPRL1CNR2S1PR1SGPL1
SCHEMBL9013393 0.81 MEN1 (0.34) MAPTOPRL1CYP3A4CYP2C8S1PR3
SCHEMBL7736458 0.81 CYP2C9 (0.52) CYP2C9MAPTALDH1A1LMNAOPRL1
SCHEMBL7736461 0.81 CYP2C9 (0.52) CYP2C9MAPTALDH1A1LMNAOPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 EP disclosed
US-5468421-A Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1995-11-21 US disclosed
EP-0568040-A1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1993-11-03 EP disclosed