Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377873 | 0.85 | ESR1 (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2TP53 | |
| SCHEMBL6493882 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL9013519 | 0.81 | KDM4E (0.55) | KDM4ENT5EALDH1A1HPGDKMT2A | |
| SCHEMBL632828 | 0.79 | LMNA (0.64) | KDM4EALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL5476158 | 0.78 | LMNA (0.58) | KDM4ENT5EHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL28348177 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL30230259 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL5479399 | 0.77 | POLB (0.47) | KDM4EALDH1A1HSD17B10PTGS2MAPT | |
| SCHEMBL27931127 | 0.76 | KDM4E (0.44) | KDM4ENT5EALDH1A1HPGDKMT2A | |
| SCHEMBL5479456 | 0.76 | HIF1A (0.42) | KDM4ENT5EALDH1A1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |