Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118153 | 0.85 | ESR2 (0.52) | KDM4EKMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL9013632 | 0.81 | KDM4E (0.55) | KDM4ENT5EKMT2AALDH1A1HPGD | |
| SCHEMBL9013541 | 0.79 | ABCG2 (0.54) | KDM4EKMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6494121 | 0.79 | ALDH1A1 (0.51) | KDM4EKMT2AALDH1A1HPGDTP53 | |
| SCHEMBL602293 | 0.78 | LMNA (0.64) | KDM4EKMT2AHPGDTP53NPSR1 | |
| SCHEMBL5483659 | 0.74 | PIK3CA (0.43) | — | |
| SCHEMBL6637129 | 0.74 | FABP3 (0.57) | KDM4EKMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL338452 | 0.73 | CLK4 (0.64) | KDM4EKMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL601281 | 0.73 | HSD17B10 (0.54) | KDM4ENT5EKMT2AALDH1A1HPGD | |
| SCHEMBL5483100 | 0.73 | ABCG2 (0.71) | KDM4EKMT2AALDH1A1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |