Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727177 | 0.98 | ALDH1A1 (0.62) | ALDH1A1TDP1POLBHRH1CACNA1F | |
| SCHEMBL6271031 | 0.74 | POLB (0.50) | ALDH1A1TDP1POLBHRH1CACNA1F | |
| SCHEMBL7860635 | 0.74 | POLB (0.50) | ALDH1A1TDP1POLBHRH1CACNA1F | |
| SCHEMBL20792002 | 0.74 | POLB (0.50) | ALDH1A1TDP1POLBHRH1CACNA1F | |
| SCHEMBL1461591 | 0.74 | TDP1 (0.54) | ALDH1A1TDP1POLBHRH1CACNA1F | |
| SCHEMBL14353612 | 0.74 | POLB (0.54) | ALDH1A1TDP1POLBHRH1CACNA1F | |
| SCHEMBL3100182 | 0.74 | TSHR (0.59) | ALDH1A1TDP1POLBHRH1CACNA1F | |
| SCHEMBL11885823 | 0.72 | TDP1 (0.63) | TDP1POLBHRH1HRH3CNR1 | |
| SCHEMBL14524241 | 0.70 | POLB (0.67) | TDP1POLBHRH1HRH3CNR1 | |
| SCHEMBL5333408 | 0.70 | POLB (0.67) | TDP1POLBHRH1HRH3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571521-A | Composition containing silver ammonium phenytoin complex and a phenytoin and use of said composition | LASKER SIGMUND E (US) | 1996-11-05 | — | — | US | claimed |
| US-5571521-A | Composition containing silver ammonium phenytoin complex and a phenytoin and use of said composition | LASKER SIGMUND E (US) | 1996-11-05 | — | — | US | disclosed |