Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588886 | 0.92 | KDM4E (0.58) | LMNAMAPTTSHRKDM4EMAPK1 | |
| Maleic Acid SCHEMBL9013664 | 0.89 | HTR1A (0.50) | — | |
| Fumaric Acid SCHEMBL9013669 | 0.89 | HTR1A (0.50) | — | |
| Maleic Acid SCHEMBL9013486 | 0.89 | ESR1 (0.48) | ESR1 | |
| Fumaric Acid SCHEMBL9013491 | 0.89 | ESR1 (0.48) | ESR1 | |
| SCHEMBL9013604 | 0.85 | MEN1 (0.52) | ESR1 | |
| Hydrochloric Acid SCHEMBL9013338 | 0.85 | ESR1 (0.64) | ESR1 | |
| Hydrochloric Acid SCHEMBL9013522 | 0.84 | ESR1 (0.53) | ESR1 | |
| Fumaric Acid SCHEMBL9013612 | 0.84 | KDM4E (0.50) | LMNAMAPTTSHRKDM4EMAPK1 | |
| Maleic Acid SCHEMBL9013610 | 0.84 | KDM4E (0.50) | LMNAMAPTTSHRKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |